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Vacunas contra la COVID-19 variante JN.1 ya están disponibles en Colombia: Pfizer y Moderna lideran la inmunización
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Como parte de las acciones para mitigar el impacto de la circulación del virus SARS-CoV-2, el Ministerio de Salud y Protección Social anunció la disponibilidad de vacunas específicas contra la variante JN.1 en todo el territorio nacional. Se trata de los biológicos Comírnaty JN.1 de Pfizer y Spikevax JN.1 de Moderna, que ya están siendo distribuidos a las entidades territoriales del país.
En total, el Gobierno nacional adquirió 198.800 dosis de Pfizer Comírnaty JN.1 y 20.400 dosis del laboratorio Moderna Spikevax JN.1, las cuales están siendo asignadas conforme a la capacidad de almacenamiento y control de cada territorio, en el marco del Plan Nacional de Vacunación.
Indicaciones técnicas y población objetivo
Las nuevas vacunas cuentan con lineamientos técnicos específicos que determinan su uso según edad, estado clínico y antecedentes vacunales. En el caso de Pfizer Comírnaty JN.1, esta está indicada para:
- Gestantes mayores de 12 años
- A partir de la semana 12 de embarazo
- Que hayan recibido su última dosis hace seis meses o más, o que no cuenten con ninguna dosis previa contra la COVID-19.
Por su parte, la vacuna de Moderna Spikevax JN.1 está autorizada para la población a partir de los 6 meses de edad. Además de las gestantes y los niños, el Ministerio priorizó a los siguientes grupos poblacionales para la aplicación de una dosis adicional:
- Personas mayores de 60 años: deben recibir la vacuna al menos seis meses después de su última dosis.
- Personas con comorbilidades: quienes tengan condiciones que aumentan el riesgo de complicaciones graves por COVID-19 deben vacunarse con una dosis adicional después de seis meses de su última dosis.
- Talento humano en salud: el personal sanitario debe recibir la dosis una vez hayan transcurrido seis meses o más desde su última inmunización.
Para optimizar el uso de estas vacunas, el Ministerio establece que, una vez se abre un vial multidosis y considerando su vida útil, las dosis deben aplicarse en primer lugar a los grupos priorizados. No obstante, también pueden administrarse a cualquier persona que desee vacunarse, siempre que cumpla con los criterios técnicos establecidos.
Recomendaciones clínicas: vacunación post-COVID y coadministración
El Ministerio de Salud reiteró que haber tenido la infección no representa una contraindicación para recibir la vacuna. Así lo manifestó el ministro Guillermo Alfonso Jaramillo, quien enfatizó: “Es importante tener en cuenta que las personas que han contraído COVID-19 pueden inocularse con las vacunas disponibles en el país una vez se hayan recuperado; no se debe retrasar ninguna dosis. Tener síntomas prolongados no es una contraindicación para recibir la vacuna y esta puede aplicarse simultáneamente con la vacuna contra la influenza, así como con todas las demás vacunas de la infancia. No olvidemos que la COVID-19 mantiene su circulación en todo el mundo”.
Vigilancia epidemiológica y comportamiento genómico del virus
Por otra parte, el seguimiento genómico en Colombia continúa activo a través del Instituto Nacional de Salud (INS), que en su programa de caracterización genómica del SARS-CoV-2 mantiene vigilancia constante sobre las variantes en circulación. La variante JN.1 se destaca como una de las predominantes durante 2024.
A nivel global, la Organización Mundial de la Salud (OMS) también ha clasificado a JN.1 como una de las variantes que siguen circulando junto a otras de preocupación como LP8.1, KP3 y XEC, entre otras. Se ha documentado que la vacuna JN.1 puede brindar protección cruzada frente a varias de estas cepas, lo que refuerza su valor estratégico en la campaña de inmunización.
De acuerdo con el boletín epidemiológico del Instituto Nacional de Salud, con corte a la semana 16 (19 de abril de 2025), se han notificado 2.151 casos de COVID-19 al sistema nacional de vigilancia (SIVIGILA), con un total de 42 defunciones registradas.
El 82,5 % de los fallecimientos (33 casos) corresponden a personas mayores de 60 años. Estas defunciones se distribuyen geográficamente de la siguiente forma:
- Bogotá: 6 casos
- Cauca: 2 casos
- La Guajira, Meta, Santander, Sucre y Valle del Cauca: 1 caso en cada uno
Estos datos confirman la persistencia del virus en el país y la necesidad de mantener la vigilancia epidemiológica y la cobertura vacunal en los grupos de mayor riesgo.
Marco normativo actual
El proceso de vacunación y la aplicación de estas nuevas dosis se encuentran enmarcados en la Resolución 2495 del 9 de diciembre de 2024, que establece los lineamientos técnicos y operativos para la prevención de la COVID-19 en Colombia. Esta norma regula aspectos como:
- Las condiciones para la aplicación de dosis adicionales
- La priorización de grupos poblacionales
- Las combinaciones permitidas con otras vacunas del esquema nacional
Con estas nuevas adquisiciones, Colombia avanza en la consolidación de una respuesta técnica, preventiva y basada en evidencia frente a la evolución del SARS-CoV-2, reforzando la protección de los más vulnerables y asegurando la continuidad del acceso a vacunas adaptadas a las variantes actualmente en circulación.
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