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Medicamentos prometen poner freno a la enfermedad del ébola
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Luego de anunciados los resultados de un ensayo clínico donde se analizaron aproximadamente 725 pacientes con ébola a comienzos de noviembre del 2018 en la República Democrática del Congo (RDC), como parte de la respuesta de emergencia a un brote de ébola en las provincias de Kivu del Norte e Itur.
Los investigadores demostraron en el ensayo la eficacia de dos nuevos medicamentos contra el ébola. El REGN-EB3 y el mAb114, los cuales pueden ser claves en la lucha contra esta enfermedad y permitirían convertir una patología “aterradora” en una infección “tratable”.
Nuevos medicamentos para combatir el Ébola
Los nuevos tratamientos fueron probados con enfermos del terrible brote que azota a la República Democrática del Congo y que ya se ha cobrado la vida de más de 1.800 personas.
En la investigación coordinada por la Organización Mundial de la salud (OMS), se pudo comprobar que las tasas de supervivencia de los pacientes con la enfermedad fueron mucho más efectivas cuando los pacientes reciben tratamiento en una etapa temprana, es decir, antes que el virus se expanda a través del cuerpo. Dicen los especialistas, agregando que “en estos pacientes, la carga viral es baja”.
Así mismo, también se probaron otros medicamentos entre ellos el ya conocido ZMapp y el remdesivir.
También puede leer: inicia compra de vacuna contra el ébola
Análisis del ensayo clínico contra el Ébola
Dicho ensayo ha sido dirigido por un equipo que se reúne periódicamente para controlar los datos de seguridad y eficacia y hacer recomendaciones sobre el estudio. Al revisarse los resultados provisionales, el equipo encontró que el porcentaje de mortalidad al emplearse REGN-EB3 y mAb114 era del 27 y el 34 por ciento, respectivamente, mientras que en el caso del ZMapp era del 49 y el del remdesivir del 53, ha explicado Fauci, director del Instituto Nacional de Alergia y Enfermedades Infecciosas (NIAID), entidad dependiente de los Institutos Nacionales de la Salud de EE. UU. (NIH) y uno de los impulsores del exitoso ensayo.
vacuna del ébola no puede ser reemplazada
Por otra parte, Fauci ha explicado que en ningún caso se podrían reemplazar las vacunas que se están utilizando contra la enfermedad (rVSV-ZEBOV-GP en RDC) ya que los primeros se emplean para personas infectadas y las segundas son para prevenir la enfermedad.
Finalmente, Mike Ryan, jefe del programa de emergencias de la OMS, ha dicho que las noticias son muy buenas pero los fármacos no son suficientes, por sí solos, para poner fin a la enfermedad. “Las noticias de este lunes son fantásticas. Nos da una nueva herramienta contra el ébola, pero sola no lo detendrá”, a informado a un diario estadounidense.
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